Ciclesonide, a Novel Inhaled Steroid, Does Not Affect Hypothalamic-Pituitary-Adrenal Axis Function in Patients With Moderate-to-Severe Persistent Asthma

Article ID	Journal	Published Year	Pages	File Type
9161693	Chest	2005	11 Pages	PDF

Abstract

Treatment with moderate and high doses of CIC does not result in hypothalamic-pituitary-adrenal-axis suppression as compared with PBO.

Keywords

CFC ACTH Desisobutyryl-ciclesonide PBO AUC0–24h HFA MDI Fluticasone ICS OCs CIC ANCOVA Asthma analysis of covariance Metered-dose inhaler Ciclesonide confidence interval Fluticasone propionate Hypothalamic-pituitary-adrenal axis HPA adrenocorticotrophic hormone Hydrofluoroalkane hypothalamic-pituitary-adrenal Placebo chlorofluorocarbon cortisol oral corticosteroid Inhaled corticosteroid

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Ciclesonide, a Novel Inhaled Steroid, Does Not Affect Hypothalamic-Pituitary-Adrenal Axis Function in Patients With Moderate-to-Severe Persistent Asthma

Authors

Szefler MD, Rohatagi PhD, MBA, Williams MD, Lloyd BS, Kundu PhD, Banerji MD,