Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9161891 | Chest | 2005 | 8 Pages |
Abstract
COPD is associated with an increased nasal concentration of the neutrophil chemoattractant protein IL-8, the degree of which reflects that present in the lower airway. A relationship between lower airway bacterial colonization, postnasal drip, and higher nasal bacterial load may suggest a mechanism underlying this finding. This study is the first to report a correlation between the degree of upper and lower airway inflammation in COPD
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Authors
Hurst MB, ChB, Wilkinson MB, BS, Perera MB, BS, Donaldson PhD, Wedzicha MD,