Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9169250 | Heart Rhythm | 2005 | 8 Pages |
Abstract
Asymptomatic individuals with a Brugada-type ECG generally have a better prognosis than their symptomatic counterparts, but a subgroup of these individuals may have a poor prognosis. Severe Na channel dysfunction as a result of SCN5A mutations may not be sufficient to cause symptoms or arrhythmias in patients with Brugada syndrome, suggesting unknown factors or modifier genes influence arrhythmogenesis.
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Authors
Hisataka MD, PhD, Naomasa MD, PhD, Koji MD, PhD, Yasuhiro MD, PhD, Yasuo MD, PhD, Tetsuo MD, Takeru MD, Akira MD, PhD, Minoru MD, PhD, Ichiro MD, PhD, Hiroyuki MD, PhD,