Changes in venous refilling time from childhood to adulthood in subjects with apparently normal veins

To our knowledge, this is the first time the physiologic changes of venous calf pump function have been documented in a longitudinal study in young volunteers with healthy veins. The median venous refilling time successively lengthened, corresponding to a maturing of the venous calf pump function during adolescence and then stayed on a stable level. Therefore, measurements of venous calf pump function are not a means for assessing malfunction of the venous system during childhood and adolescence.