Relationship of C-reactive protein with components of the metabolic syndrome in normal-weight and overweight elderly

In normal-weight women, ln-CRP was significantly associated with BMI, PAI-1, serum insulin, and HDL-cholesterol. In overweight women, however, these relationships were weak and not statistically significant. Findings were similar in men, although less pronounced than in women. Our data suggest that the role of CRP in the metabolic syndrome is modified by the amount of body fat.