| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9185005 | Thrombosis Research | 2005 | 9 Pages |
Abstract
C-terminal lysines are necessary for high-affinity binding of plasminogen to platelets and for platelet-supported plasmin generation. The origin of the C-lysines is not clear, but they may result from a direct effect of thrombin, rather than an intermediate enzyme such as plasmin.
Keywords
CPBtPAEACACarboxypeptidaseTRAPPMSFADPPGE1BSAKcatbovine serum albuminSDS-PAGEcatalytic constantDissociation constantBinding capacitytissue plasminogen activatorphenylmethyl-sulfonyl fluorideLysineMichaelis constantProstaglandin E1PlasminogenPlateletsthrombin receptor activating peptidecarboxypeptidase B
Related Topics
Health Sciences
Medicine and Dentistry
Cardiology and Cardiovascular Medicine
Authors
McDonald K. III, Paula K. Merryman, Ann M. Cullinane,