| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9211463 | Journal of Endodontics | 2005 | 5 Pages |
Abstract
This study assessed the efficacy of a triple antibiotic paste in the disinfection of immature dog teeth with apical periodontitis. The canals were sampled before (S1) and after (S2) irrigation with 1.25% NaOCL and after dressing with a triple antibiotic paste (S3), consisting of metronidazole, ciprofloxacin, and minocycline. At S1, 100% of the samples cultured positive for bacteria with a mean CFU count of 1.7 Ã 108. At S2, 10% of the samples cultured bacteria-free with a mean CFU count of 1.4 Ã 104. At S3, 70% of the samples cultured bacteria-free with a mean CFU count of only 26. Reductions in mean CFU counts between S1 and S2 (p < 0.0001) as well as between S2 and S3 (p < 0.0001) were statistically significant. These results indicate the effectiveness of a triple antibiotic paste in the disinfection of immature teeth with apical periodontitis.
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Authors
William DDS, MS, Fabricio DDS, MSc, PhD, Linda DDS, PhD, Asgeir DDS, MS, Martin DMD,