| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9215782 | Medical Journal Armed Forces India | 2005 | 6 Pages |
Abstract
Longer duration of CPB initiates plasmin generation through heparin, which raises the PAI-1-tPA complex and thereby down regulating the functions of platelets. This suggests a link between duration of CPB, bleeding, platelet dysfunction and fibrinolysis. Hence serial estimations of the levels of GMP-140 and tPA can predict severe bleeding.
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Authors
SJ Retd, MK Unni, N Retd, Ramji AVSM, VSM, PHS,