Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9222143 | Actas Dermo-Sifiliográficas | 2005 | 17 Pages |
Abstract
In our series, a perfect correlation was seen between the findings of serum electrophoresis and the immunohistochemistry of the skin lesions with regard to the type of immunoglobulin and the immunoglobulin light chain restriction produced by the neoplastic plasma cells. Patients with multiple myeloma have a very short survival period once specific skin lesions appear, regardless of the therapy administered. The deletion of the rb 1 gene may be a prognosis marker to identify those patients with especially aggressive forms of multiple myeloma.
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Authors
Luis Requena,