| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9222716 | Actas Dermo-Sifiliográficas | 2005 | 7 Pages |
Abstract
We managed to silence the expression of CD9 and CD151 using iRNA techniques in the A375 melanoma cell line. The reduction in CD9 caused the inhibition of cell motility, while the interference with CD151 expression had a more moderate effect. This data indicates that the knockdown of tetraspanins may be a future target for the treatment of melanoma.
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Authors
Pablo F. Peñas, MarÃa A. GarcÃa-López, Olga Barreiro del RÃo,