| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9225584 | Journal of Allergy and Clinical Immunology | 2005 | 8 Pages |
Abstract
These data suggest that keratinocyte-derived costimulation mediated by B7-1 but not B7-2 results in the emergence of TH2-lymphocyte immune responses to TH1 haptens. Because human keratinocytes have been noted to express B7-1-like molecules in certain inflammatory skin diseases, this model may be important in understanding the pathophysiology of TH2-lymphocyte-mediated skin diseases such as atopic dermatitis.
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Authors
Robert PhD, Irina MD, PhD, Adnan MD, PhD, Constantine G. PhD, Richard K. PhD, Anthony A. MD,