Respiratory syncytial virus infection in the absence of STAT1 results in airway dysfunction, airway mucus, and augmented IL-17 levels

Article ID	Journal	Published Year	Pages	File Type
9226781	Journal of Allergy and Clinical Immunology	2005	8 Pages	PDF

Abstract

These results show that STAT1 has an important regulatory role in RSV-induced alteration of airway function.

Keywords

AHR IL-23 ECP BAL RSV IL-17 STAT periodic acid–Schiff inflammation Rodent Cytokines bronchoalveolar lavage Signal transducer and activator of transcription Mucus knockout PAS wild-type plaque-forming units Respiratory syncytial virus Viral Airway hyperresponsiveness Eosinophil cationic protein pfu

Related Topics

Life Sciences Immunology and Microbiology Immunology

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Respiratory syncytial virus infection in the absence of STAT1 results in airway dysfunction, airway mucus, and augmented IL-17 levels

Authors

Koichi MD, PhD, Joan E. MD, PhD, Weisong PhD, Robert D. MD, Samuel B. MD, Jay K. MD, Patricia J. MD, James R. MD, Kasia MS, Jamye F. BS, Sandra J. MS, Daphne BS, Barney S. MD, PhD, R. Stokes MD,