Physiologic assessment of allergic rhinitis in mice: Role of the high-affinity IgE receptor (FcɛRI)

These data indicate that FcɛRI is essential to development of an early-phase nasal response and contributes to the development of the late-phase nasal response. These invasive and noninvasive approaches provide new opportunities to evaluate the mechanisms underlying the development of nasal responses to allergen and to assess various therapeutic interventions.