Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9227222 | Journal of Allergy and Clinical Immunology | 2005 | 9 Pages |
Abstract
Eosinophils express at least 2 potent mediators (IL-1β and TGF-β) that induce a fibrogenic fibroblast phenotype, strongly supporting a role for the eosinophil in the dysregulation of extracellular matrix homeostasis and consequent tissue remodeling and fibrosis in eosinophil-associated diseases.
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Authors
Ignatius PhD, Sameer K. MD, Bruce M. MD, Yasuji MD, PhD, John MD, Steven J. PhD,