Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9236715 | Clinical Immunology | 2005 | 9 Pages |
Abstract
Our data show that the immunoinflammatory features of ASST-induced wheals involve a prevalent role of lymphocytes (with a mixed Th1/Th2 response), with strong neutrophil infiltration and activity and involvement of the chemokine pathway. We interpreted the finding of inflammatory cells and mediator up-regulation in uninvolved CIU skin as a sign of prolonged and widespread “urticarial status”.
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Authors
Marzia Caproni, Barbara Giomi, Walter Volpi, Lucilla Melani, Emiliano Schincaglia, Donatella Macchia, Mariangela Manfredi, Alberino D'Agata, Paolo Fabbri,