Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9238013 | Digestive and Liver Disease | 2005 | 8 Pages |
Abstract
These results indirectly confirm that, in vivo, alpha-smooth muscle actin expression is a reliable marker of hepatic stellate cells activation which precedes fibrous tissue deposition even in the setting of recurrent HCV chronic hepatitis after liver transplantation, and it could be useful to identify the earliest stages of hepatic fibrosis and monitoring the efficacy of the therapy. In the presence of advanced cirrhosis other factors, rather than alpha-smooth muscle actin-positive hepatic stellate cells, may sustain fibrosis deposition.
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Authors
G. Carpino, S. Morini, S. Ginanni Corradini, A. Franchitto, M. Merli, M. Siciliano, F. Gentili, A. Onetti Muda, P. Berloco, M. Rossi, A.F Attili, E. Gaudio,