Tumeurs à rénine

Primary reninism is a rare disease (about 100 published cases) usually caused by a juxtaglomerular cell renal tumour or, in some cases, by an extrarenal malignant tumour. The clinical presentation is an elevated blood pressure with secondary aldosteronism, and a very high level of plasmatic renin concentration. The CT-scan shows a hypo-intense cortical renal image and absence of renal artery stenosis or cortical infarct. The tumour resection suppresses the secondary aldosteronism and generally results in a relief or an improvement of the hypertension.