| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9239690 | Journal de Gynécologie Obstétrique et Biologie de la Reproduction | 2005 | 4 Pages |
Abstract
We report the case of a newborn presenting an agenesis of corpus callosum (ACC) discovered in the prenatal period and initially related to cocaine exposure during the first trimester of gestation. The cytogenetic analysis revealed a trisomy 8 mosaicism. The putative role of prenatal cocaine exposure and mosaicism for chromosome 8 in ACC are discussed. This report emphasizes the specific analysis of chromosome 8 by using fluorescence in situ hybridization as a complement to routine cytogenetic analysis for prenatal diagnosis of ACC.
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Authors
E. Gonzales, L. Caeymaex, A. Aboura, M. Vial, J. de Laveaucoupet, P. Labrune, G. Tachdjian,