| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 925160 | Brain and Cognition | 2006 | 6 Pages |
Abstract
The functional link between the amygdala and hippocampus in humans has not been well documented. We examined the effect of unpleasant loud noise on hippocampal and amygdaloid activities during picture encoding by means of fMRI, and on the correct response in humans. The noise reduced activity in the hippocampus during picture encoding, decreased the correct response and increased the activity of the amygdala. A path diagram using structural equation modeling suggested that hippocampus activity might be depressed by high amygdala activity. Therefore, noise should diminish memory by reducing hippocampal activity, which might be depressed by high amygdala activity.
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Authors
Yoshiyuki Hirano, Masafumi Fujita, Kazuko Watanabe, Masami Niwa, Toru Takahashi, Masayuki Kanematsu, Yasushi Ido, Mihoko Tomida, Minoru Onozuka,