Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9253542 | Journal of Hepatology | 2005 | 7 Pages |
Abstract
EE causes a cell cycle block before S-phase. The reduction of the cdk2 kinase activity, essential for G1/S-transition, might be involved in the cell cycle block. Also, EE treatment results in p53 activation and upregulation of the cdk inhibitor p21 that might contribute to the G1 arrest.
Keywords
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Authors
Lena Koroxenidou, Lena C.E. Ohlson, Inger Porsch Hällström,