| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9253744 | Journal of Hepatology | 2005 | 6 Pages |
Abstract
This study demonstrates that the development of hyperdynamic splanchnic circulation and the formation of portal-systemic collateral vessels in portal hypertensive rats are angiogenesis-dependent processes that can be markedly inhibited by blockade of the VEGF signaling pathway. Therefore, modulation of angiogenesis may represent a potential target in the treatment of portal hypertension.
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Authors
Mercedes Fernandez, Marc Mejias, Bernhard Angermayr, Juan Carlos Garcia-Pagan, Juan Rodés, Jaime Bosch,