Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9253895 | Journal of Hepatology | 2005 | 9 Pages |
Abstract
Cholangiocytes respond to GH with production and release of IGF1 that modulates cell proliferation by transduction pathways involving IGF1-R, IRS1/2 and both ERK and PI3-kinase pathways. The biliary epithelium is a target of GH/IGF1 liver axis.
Keywords
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Authors
Domenico Alvaro, Veronica Drudi Metalli, Gianfranco Alpini, Paolo Onori, Antonio Franchitto, Barbara Barbaro, Shannon S. Glaser, Heather Francis, Alfredo Cantafora, Ida Blotta, Adolfo Francesco Attili, Eugenio Gaudio,