| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9254350 | Journal of Hepatology | 2005 | 8 Pages |
Abstract
This is the first demonstration that a specific COX-2 inhibitor, celecoxib, possesses striking chemopreventive activity, inhibiting preneoplastic lesions during hepatocarcinogenesis in vivo, suggesting that celecoxib effects are mediated by PGE2-independent mechanisms.
Keywords
GGTCOXPCNANSAIDhptDenSelective cyclooxygenase-2 inhibitorPARPGST-P2-AAFPGSHepatocarcinogenesis2-acetylaminofluoreneγ-glutamyltranspeptidaseProliferating Cell Nuclear AntigencyclooxygenaseNon-steroidal anti-inflammatory drugsdiethylnitrosamineglutathione S-transferase placental formProstaglandinsChemoprevention
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Authors
Lucrecia Márquez-Rosado, MarÃa Cristina Trejo-SolÃs, Claudia MarÃa GarcÃa-Cuéllar, Saúl Villa-Treviño,