The contribution of the inferior parietal cortex to spoken language production

This functional MRI study investigated the involvement of the left inferior parietal cortex (IPC) in spoken language production (Speech). Its role has been apparent in some studies but not others, and is not convincingly supported by clinical studies as they rarely include cases with lesions confined to the parietal lobe. We compared Speech with non-communicative repetitive tongue movements (Tongue). The data were analyzed with both univariate contrasts between conditions and probabilistic independent component analysis (ICA). The former indicated decreased activity of left IPC during Speech relative to Tongue. However, the ICA revealed a Speech component in which there was correlated activity between left IPC, frontal and temporal cortices known to be involved in language. Therefore, although net synaptic activity throughout the left IPC may not increase above baseline conditions during Speech, one or more local systems within this region are involved, evidenced by the correlated activity with other language regions.

► A role for parietal cortex in spoken language is often assumed. ► There is only limited evidence to support this. ► We contrasted speech production with non-communicative tongue movements. ► Subtractive contrasts and probabilistic independent component analysis were used. ► Only the latter confirmed inferior parietal cortex involvement in speech production.