| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9254484 | Journal of Hepatology | 2005 | 11 Pages |
Abstract
HSCs from human cirrhotic livers show fibrogenic and contractile features. However, the current model of HSCs activated in culture does not exactly reproduce the activated phenotype found in cirrhotic human livers.
Keywords
ECMαSMAHSCsMCAMTIMP-1PDGFAT1FBSSmooth Muscle Alpha ActinTGF-β1BKCaAngiotensin IIPAITransforming growth factor β1Ang IIMicroarrayfetal bovine serumHepatic stellate cellsplatelet-derived growth factorCell activationLiver fibrosisExtracellular matrixmelanoma cell adhesion moleculePlasminogen activator inhibitor type 1Angiotensin receptor type 1Portal hypertensionCollagen
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Authors
Pau Sancho-Bru, Ramón Bataller, Xavier Gasull, Jordi Colmenero, Valeriya Khurdayan, Arcadi Gual, Josep M. Nicolás, Vicente Arroyo, Pere Ginès,