| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9254851 | Journal of Hepatology | 2005 | 7 Pages |
Abstract
Integrin activation in isolated hepatocytes contributes to the activation of ILK, phosphorylation of Akt on serine residue 473, and inhibition of apoptosis. Integrin signaling through the ILK-phospho Akt pathway protects isolated hepatocytes from apoptosis. This notion may potentially be applied to render the transplantation of hepatocytes more effective.
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Authors
Gabrielle G.M. Pinkse, Reshma Jiawan-Lalai, Jan A. Bruijn, Emile de Heer,