| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9257609 | Critical Reviews in Oncology/Hematology | 2005 | 24 Pages |
Abstract
Numerous case-control and prospective studies have been conducted on folate and colorectal cancer, which all together miss a clinical bottom line. The recommendation of folate intake to prevent colorectal cancer is therefore not evidence-based.
Keywords
deoxyuridylateMTHFRPTEDnmtMTHFR polymorphismPteroic acidSAMRDADTMPPteGlu5-methyl-tetrahydrofolate7,8-dihydrofolate95% CIDfES-adenosylmethionineFolic acidrecommended daily allowanceRelative riskdUMPColorectal carcinogenesis95% confidence intervalFolateDNA methylationMethylenetetrahydrofolate reductaseodds rationicotinamide adenine dinucleotide phosphatePrevention
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Authors
L. Cornelius Bollheimer, Roland Buettner, Anja Kullmann, Frank Kullmann,