Evaluation of platelet parameters in healthy apheresis donors using the ADVIA 120™

Platelet apheresis is accepted as a safe procedure and no clinically important change is observed after apheresis. The ADVIA 120™ provides both an accurate platelet count and parameters describing platelet morphology and function. We studied the changes in platelet parameters of 35 healthy apheresis donors using the ADVIA 120. The mean platelet component value did not change after apheresis but the value of the platelet count was low and this reduction could be due to activation of platelets. We conclude that no remarkable changes were noted except the reduction in platelet numbers and plateletcrit which were expected to return to normal values in a few days.