Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9258959 | Transfusion and Apheresis Science | 2005 | 7 Pages |
Abstract
We tracked the results of 394 manual or automatic red blood cell exchanges done with a cell separator in 20 sickle cell patients at high risk for recurrent complications. Over an average of 6 years, none of the patients developed complications related to the procedure or to the increased blood use. It was safe and effective in preventing complications of sickle cell disease, and if done automatically, reduced iron overload. Ferritin levels also decreased in patients treated with automatic red blood cell exchange. Furthermore, using Single Donor Red Blood Cell units (SDRC) we reduced the potential exposure to transfusion transmitted infectious diseases (TTI).
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Authors
Sergio Cabibbo, Carmelo Fidone, Giovanni Garozzo, Agostino Antolino, Giovanna Oriella Manenti, Francesco Bennardello, Vincenzo Licitra, Salvatore Calabrese, Francesco Costantino, Simone Travali, Roberto Distefano, Pietro Bonomo,