Total serum IgE: Adult reference values in Valencia (1981-2004). Usefulness in the diagnosis of allergic asthma and rhinitis

Our data confirm the current validity of the reference values obtained in 1981, which continue to be significantly different from those of the UniCAP® method for Swedish donors. The population of allergic subjects can be divided into two subgroups: subjects with total IgE levels similar to those of the donors, which we refer to as LRs, and which represent 44 % of all allergic subjects, and a second subgroup with total IgE values above those of the donors (HRs), who would therefore be the only subjects that would be identified by individual serum IgE study.