| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9261575 | Autoimmunity Reviews | 2005 | 7 Pages |
Abstract
Inhibitors of 3-hydroxy-3methylglytaryl coenzyme A (HMG-CoA) reductase or statins are effective lipid lowering drugs widely used in cardiovascular disease. In the recent years, pleotropic effects of statins have been reported, which include anti-inflammatory and immunomodulatory properties. This review discusses the anti-inflammatory and immunomodulatory roles of statins and their possible use for the treatment of other inflammatory diseases or conditions with the involvement of the immune system.
Keywords
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Immunology
Authors
Victor S. Gurevich, Ora Shovman, Liat Slutzky, Pier Luigi Meroni, Yehuda Shoenfeld,