Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9261659 | Autoimmunity Reviews | 2005 | 6 Pages |
Abstract
This article reviews the role of CD20 antigen in B cell function and the effectiveness and limits of passive immunotherapy with anti-CD20 monoclonal antibody (Rituximab) in the treatment of autoimmune (or immune-mediated) diseases. Active immunotherapy is a more feasible way to control these chronic diseases. A peptide that mimics the CD20 epitope recognized by Rituximab is employed to stimulate the host immune response against CD20.
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Authors
Federico Perosa, Elvira Favoino, Maria Antonietta Caragnano, Marcella Prete, Franco Dammacco,