Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9262469 | Clinical Microbiology Newsletter | 2005 | 7 Pages |
Abstract
Staphylococcus aureus is a well-known pathogen that is responsible for causing a myriad of human illnesses, including skin infections, food poisoning, life-threatening shock, and various autoimmune disorders. A number of virulence factors are produced by this organism, including staphylococcal enterotoxins (SEs) and the related toxic shock syndrome toxin 1 (TSST-1), that possess superantigenic activity. Part II of this article will review the various in vitro and in vivo models that are available for studying SEs and TSST-1, thus providing invaluable tools for understanding how these toxins work and subsequently countering them via experimental vaccines and therapeutics.
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Authors
Bradley G. Ph.D., Teresa Ph.D.,