Article ID Journal Published Year Pages File Type
9262909 Current Opinion in Immunology 2005 7 Pages PDF
Abstract
The discovery that Peyer's patch and lymph node development is regulated by the collaboration between fetal hematopoietic cells and mesenchymal cells has thrown new light on our understanding of the mechanisms underlying the formation of lymphoid organs. Lymphoid tissue inducer cells trigger a coordinated series of events leading to cell clustering and changes in gene expression and differentiation. Nevertheless, many questions regarding the origin, recruitment and fate of the inducer cells and cellular crosstalk with neighboring cells remain unanswered.
Related Topics
Life Sciences Immunology and Microbiology Immunology
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