Article ID Journal Published Year Pages File Type
9267797 Journal of Autoimmunity 2005 12 Pages PDF
Abstract
From our previous report on DC differentiation defects in BB rats (only differing in iddm2) and the present report, we deduce that the abnormal apoptosis and low MHC class II expression is linked to iddm2. The reduced T cell stimulatory capacity is linked to other genes on chromosome 4 (candidate gene: iddm4). The reduced IL-10 production has a complex linkage pattern.
Related Topics
Life Sciences Immunology and Microbiology Immunology
Authors
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