Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9267797 | Journal of Autoimmunity | 2005 | 12 Pages |
Abstract
From our previous report on DC differentiation defects in BB rats (only differing in iddm2) and the present report, we deduce that the abnormal apoptosis and low MHC class II expression is linked to iddm2. The reduced T cell stimulatory capacity is linked to other genes on chromosome 4 (candidate gene: iddm4). The reduced IL-10 production has a complex linkage pattern.
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Immunology
Authors
Vinod Sommandas, Elizabeth A. Rutledge, Brian Van Yserloo, Jessica Fuller, Ã
ke Lernmark, Hemmo A. Drexhage,