Article ID Journal Published Year Pages File Type
9271741 Osteoarthritis and Cartilage 2005 8 Pages PDF
Abstract
TLR2 is expressed in human articular cartilage and is upregulated by proarthritic agents including IL-1β and fibronectin fragments. Signaling through TLR is a novel pro-inflammatory mechanism in osteoarthritis and targeting of these signaling pathways may be of value in treatment of degenerative joint disease.
Keywords
Related Topics
Health Sciences Medicine and Dentistry Immunology, Allergology and Rheumatology
Preview
Expression and regulation of Toll-like receptor 2 by IL-1β and fibronectin fragments in human articular chondrocytes
Authors
, , , , , ,