Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9271970 | Osteoarthritis and Cartilage | 2005 | 11 Pages |
Abstract
Early-onset OA demonstrates locus and allelic heterogeneity since the identified variations were in three different collagen genes and each of the six probands had a different mutation. It is also possible that some OA cases represent the mild end of the chondrodysplasia phenotypic spectrum. The major susceptibility alleles in this form of OA, however, remain to be identified.
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Authors
E. M.D., M. M.D., I. M.D., Ph.D., J. (Med. Cand.), S.S. M.D., Ph.D., M. Ph.D., M.L. M.D., K. M.D., H. M.D., Ph.D., H.H.H. Ph.D., L. M.D., Ph.D.,