Article ID Journal Published Year Pages File Type
9273505 Seminarios de la Fundación Española de Reumatología 2005 7 Pages PDF
Abstract
Osteoporosis is treated with drugs that either stimulate bone resorption or bone formation. Combination therapy between antiresorptives drugs have nor shown greatest capacity to reduce the risk of fracture than monotherapy, furthermore the economic cost, the increase of adverse events and the influence in decreasing the adherence of treatment have lead to unrecommend this therapy. Combination or sequential therapy with antiresorptives drugs and others drugs that stimulate bone formation have been scantily evaluated. Nowadays several therapy trials are carrying out to analyse in a rigorous way their efficacy. Herein is included a comprehensive review of sequential therapy.
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