| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9273576 | Seminars in Immunology | 2005 | 6 Pages |
Abstract
Gene expression, differentiation and the specialized function of various cell types are controlled epigenetically by post-translational histone modifications. These modifications establish a “histone code” that is recognized by various regulatory proteins, thereby creating a stable pattern of gene expression. The focus of this review is to discuss how the chromatin modifications regulate immunoglobulin gene rearrangement and B cell differentiation.
Keywords
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Immunology
Authors
I-hsin Su, Alexander Tarakhovsky,