Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9273889 | Transplant Immunology | 2005 | 6 Pages |
Abstract
In this study, specific subendothelial C4d deposition was a marker for the involvement of HLA-Ab in lung allograft rejection. The patchy nature, low sensitivity, and specificity of C4d staining might limit clinical use in protocol biopsies. However, in patients with decreasing pulmonary function, refractory ACR and/or HLA-Ab, specific C4d deposition may serve as a marker of coexistent AMR.
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Authors
D.N. Ionescu, A.L. Girnita, A. Zeevi, R. Duquesnoy, J. Pilewski, B. Johnson, S. Studer, K.R. McCurry, S.A. Yousem,