| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9275263 | Antibiotiques | 2005 | 13 Pages |
Abstract
Among gram-negative bacteria, the role of β-lactamases for natural and acquired resistance is essential and more and more complex. Numerous corresponding genes located in chromosome, plasmid, integron or CR (common region) were cloned and sequenced showing a very high diversity among this type of inactivating enzymes. A lot of genetic answers were developed by bacteria after introduction of new drugs such as β-lactam antibiotics. Such adaptability of bacterial world must lead to limit the abuse of prescriptions and a better use of drugs.
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Authors
A. Philippon, G. Arlet,