Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9277959 | FEMS Immunology and Medical Microbiology | 2005 | 6 Pages |
Abstract
Intact chromosomes of 19 clinical isolates of Histoplasma capsulatum recently obtained in Argentina, Mexico and Guatemala and the laboratory reference strain G186B from Panama were analyzed using pulsed-field gel electrophoresis. Chromosomal banding patterns of the human isolates revealed 5-7 bands, ranging from 1.3 to 10Â Mbp in size. Strain G186B showed five bands of approximately 1.1, 2.8, 3.3, 5.4 and 9.7Â Mbp. Thirteen different electrokaryotypes were identified, indicating that the genome of H. capsulatum varies widely in nature, as observed previously in laboratory strains. No definite association was found between electrokaryotype and geographical or clinical source.
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Authors
Cristina Elena Canteros, MarÃa Fernanda Zuiani, Viviana Ritacco, Diego E. Perrotta, MarÃa RocÃo Reyes-Montes, Julio Granados, Gerardo Zúñiga, Maria Lucia Taylor, Graciela Davel,