Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9277963 | FEMS Immunology and Medical Microbiology | 2005 | 8 Pages |
Abstract
Fourteen Histoplasma capsulatum isolates recovered from infected bats captured in Mexican caves and two human H. capsulatum reference strains were analyzed using random amplification of polymorphic DNA PCR-based and partial DNA sequences of four genes. Cluster analysis of random amplification of polymorphic DNA-patterns revealed differences for two H. capsulatum isolates of one migratory bat Tadarida brasiliensis. Three groups were identified by distance and maximum-parsimony analyses of arf, H-anti, ole, and tub1 H. capsulatum genes. Group I included most isolates from infected bats and one clinical strain from central Mexico; group II included the two isolates from T. brasiliensis; the human G-217B reference strain from USA formed an independent group III. Isolates from group II showed diversity in relation to groups I and III, suggesting a different H. capsulatum population.
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Authors
Maria Lucia Taylor, Catalina B. Chávez-Tapia, Alberto Rojas-MartÃnez, Maria del Rocio Reyes-Montes, Mirian Bobadilla del Valle, Gerardo Zúñiga,