Article ID Journal Published Year Pages File Type
9278664 FEMS Microbiology Reviews 2005 16 Pages PDF
Abstract
Recent in silico and experimental data have shed new light on the mechanism and components of translational initiation in archaea. The available data about the structure of archaeal mRNAs, mRNA/ribosome interaction and archaeal translation initiation factors are reviewed and analyzed in the conceptual framework of the evolution of translational initiation. A model of the initiation step of translation in the Last Universal Common Ancestor of extant cells is presented and discussed.
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Life Sciences Immunology and Microbiology Applied Microbiology and Biotechnology
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