Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9283009 | Microbes and Infection | 2005 | 8 Pages |
Abstract
Group 1 and group 2 CD1 present both self and microbial lipid antigens to T cells. While group 1 CD1-restricted T cells are known for their ability to recognize mycobacterial glycolipid antigens, group 2 CD1-restricted T cells are recognized as regulatory T cells that can influence the outcome of innate and adaptive immune responses. The evidence that these T cells contribute to host defense against infectious diseases is reviewed.
Keywords
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Immunology
Authors
Markus Sköld, Samuel M. Behar,