| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9283214 | Microbes and Infection | 2005 | 9 Pages |
Abstract
It is important to evaluate HIV-1-specific immunological responses elicited by therapeutic or prophylactic vaccines using precise, standardised assays, so that the immunogenicity and putative efficacy of candidate vaccines may be compared. Different well-validated assays must be used to quantitate specific responses, to determine which particular strategies may be efficacious.
Keywords
51CrAPCHAARTIL-2RCBALCMVRVVFECTCrSOPCTLMFILPAPBMCCFSECAFICCscytometric bead arrayStandardisationEBVLDAAssayLymphocyte proliferation assayCASAHighly active anti-retroviral therapyintracellular cytokine stainingstandard operating procedurePeripheral blood mononuclear cellDendritic cellantigen presenting cellcytomegalovirusCMVstimulation indexFibroblastcytotoxic T lymphocyteMacrophageLimiting dilution assaymean fluorescence intensityVaccineImmunological responseMøEpstein barr virusrecombinant vaccinia virusLymphocytic choriomeningitis virusinterleukin-2 receptorT cell receptor
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Authors
Frances Gotch, Harvey Holmes, Nesrina Imami,