| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9283296 | Microbes and Infection | 2005 | 7 Pages |
Abstract
Graft-versus-host disease is a major complication after allogeneic bone marrow transplantation (BMT) caused by donor T cells. Immunosuppression mediated by CD4+CD25+ regulatory T cells has been shown to ameliorate such pathogenic immune responses in animal models. Here, we summarize recent findings from experimental and clinical studies and propose a model for peripheral tolerance induction after BMT.
Related Topics
Life Sciences
Immunology and Microbiology
Immunology
Authors
Petra Hoffmann, Tina J. Boeld, Biserka Piseshka, Matthias Edinger,