Clinical Experience with Single-Agent Gemcitabine Chemotherapy in Patients with Non-Small-Cell Lung Cancer in Whom Previous Chemotherapy Has Failed

Salvage, single-agent chemotherapy with gemcitabine has modest activity, is well tolerated, and yields good survival in NSCLC patients who have failed previous chemotherapy. Such single-agent therapy may therefore be suggested for use in patients with good performance status who ask for further chemotherapy, when disease progresses after cisplatin-based therapy, but especially after second-line docetaxel therapy.