| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9302965 | La Presse Médicale | 2005 | 4 Pages |
Abstract
5FU encephalopathies are rare and most often resolve favorably after treatment is stopped. Two pathophysiologic mechanisms may explain these encephalopathies: a deficit of dihydropyridine dehydrogenase, leading to an increased level of serum uracil with digestive and mucosal toxicity, or interaction of 5FU catabolites with various intracerebral metabolic pathways.
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Authors
N. Mémain, J.-F. Angellier, E. Obadia, E. Angellier, R. Chelha, R. Couprie,