Simultaneous recording of EEG and BOLD responses: A historical perspective

Electromagnetic fields as measured with electroencephalogram (EEG) are a direct consequence of neuronal activity and feature the same timescale as the underlying cognitive processes, while hemodynamic signals as measured with functional magnetic resonance imaging (fMRI) are related to the energy consumption of neuronal populations. It is obvious that a combination of both techniques is a very attractive aim in neuroscience, in order to achieve both high temporal and spatial resolution for the non-invasive study of cognitive brain function. During the last decade a number of research groups have taken up this challenge. Here, we review the development of the combined EEG–fMRI approach. We summarize the main data integration approaches developed to achieve such a combination, discuss the current state-of-the-art in this field and outline challenges for the future success of this promising approach.